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10 of 14 trials included caffeine

Alternative therapeutic thoughts in APAP hepatotoxicity Targeting APAP hepatotoxicity at the molecular level as an alternative to NAC therapy has been the goal of many research groups

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Finally, in the co-cultured model, we treated H69 cells in the insert with AA in the presence or absence of a STAT3 activator(Colivelin)and found STAT3 activation of H69 cells suppressed the THP1 mRNA expression of M1 cytokines and induced THP1 M2 gene expression